Everything about Phytochemical totally explained
Phytochemicals are plant- or fruit-derived chemical compounds. "Phytonutrients" refer to phytochemicals or compounds that come from edible plants.
Phytochemicals as therapeutics
There is evidence from laboratory studies that phytochemicals in fruits and vegetables may reduce the risk of
cancer, probably due to
polyphenol antioxidant and
anti-inflammatory effects.
Phytochemicals have been used as drugs for millennia. For example,
Hippocrates in 400 BC used to prescribe
willow tree leaves to abate fever.
Salicin, having
anti-inflammatory and pain-relieving properties, was originally extracted from the White Willow Tree and later synthetically produced to become the staple over the counter drug called
Aspirin.
The number one drug for cancer worldwide
Taxol (
paclitaxel), is a phytochemical initially extracted and purified from the
Pacific Yew Tree.
Among edible plants with health promoting phytochemicals,
Diindolylmethane, from
Brassica vegetables (
broccoli,
cauliflower,
cabbage,
kale,
Brussels sprouts) is currently used as a treatment for Recurring
Respiratory Papillomatosis tumors (caused by the
Human Papilloma Virus), it's in Phase III
clinical trials for
Cervical Dysplasia (a precancerous condition caused by the
Human Papilloma Virus) and is in clinical trials sponsored by the National Cancer Institute of the United States for a variety of cancers (breast, prostate, lung, colon, and cervical). The compound is being studied for anti-viral, anti-bacterial and anti-cancer properties through a variety of pathways and it has also been shown to synergize with
Taxol in its anti-cancer properties, making it a possible anti-cancer phytonutrient as
taxol resistance is a major problem for cancer patients.
Some phytochemicals with medicinal properties may be elements, rather than complex organic molecules.
Selenium for example is abundant in
Brassica vegetables which may have anti-viral and anti-cancer properties. In human clinical trials, selenium supplementation has been shown to reduce the
HIV viral load and may be a tool as an
adjuvant for
AIDS treatments. Selenium is a cofactor element for synthesis of
Glutathione, a potent and important
antioxidant manufactured primarily in the
liver.
There are currently many other phytochemicals with medicinal properties in clinical trials for a variety of diseases.
Lycopene, for example, from tomatoes is in clinical trials for cardiovascular diseases and prostate cancer. Human clinical trials have indicated that lycopene may enhance blood flow through the heart and clinical studies suggest anti-cancer activity against prostate cancer.
Lutein and
zeaxanthin from
spinach may affect visual performance and inhibit
macular degeneration and cataracts.
Many phytochemicals have anti-inflammatory properties in vitro, including
Turmeric and
Chia.
Inflammation is a factor in many
diseases of aging including
Alzheimer's and
Arthritis, and many artificial anti-inflammatories have unfortunate side-effects. Turmeric is also reported to be active against skin cancer (
Melanoma).
In a landmark nutritional sciences study, scientists showed a diet rich in tomatoes and broccoli may be more effective in inhibiting prostate cancer growth than a leading drug for prostate cancer. Nevertheless, following extensive evaluation of scientific and clinical evidence, the United States
Food and Drug Administration has denied applications for health claims about the benefits of tomato consumption against prostate cancer, allowing only a limited statement on food product labels. It reads:
"Very limited and preliminary scientific research suggests that eating one-half to one cup of tomatoes and/or tomato sauce a week may reduce the risk of prostate cancer. The
FDA concludes that there's little scientific evidence supporting this claim."
Clinical investigations continue to assess phytochemicals with medicinal properties.
Food processing and phytochemicals
Phytochemicals in freshly harvested plant foods may be destroyed or removed by modern processing techniques, possibly including cooking. For this reason, industrially processed foods likely contain fewer phytochemicals and may thus be less beneficial than unprocessed foods. Absence or deficiency of phytochemicals in processed foods is believed to have contributed to the increased prevalence of the above-cited preventable or treatable causes of death in contemporary society. Interestingly though,
lycopene, a phytochemical present in
tomatoes, is concentrated in processed foods such as
spaghetti sauce and
ketchup, making those foods better sources of
lycopene than fresh tomatoes.
List of foods high in phytonutrients
Foods high in phytonutrients, or
superfoods, are:
- soy – protease inhibitors, beta sitosterol, saponins, phytic acid, isoflavones
- tomato – lycopene, beta carotene, vitamin C
- broccoli – vitamin C, 3,3'-Diindolylmethane, sulphoraphane, lignans, selenium
- garlic – thiosulphonates, limonene, quercitin
- flax seeds and oil seeds – lignans
- citrus fruits – monoterpenes, coumarin, cryptoxanthin, vitamin C, ferulic acid, oxalic acid
- blueberries – tannic acid, lignans, anthocyanins
- sweet potatoes – beta carotene
- chilli peppers – capsaicin
- legumes: beans, peas, lentils – omega fatty acids, saponins, catechins, quercetin, lutein, lignans
Other foods rich in phytonutrients or superfoods
Some animal derived foods are also considered superfoods. Beginning in 2005, there has been a rapidly growing recognition of several common and exotic fruits recognized for their nutrient
richness and
antioxidant qualities, with over 900 new product introductions worldwide. More than a dozen industry publications on
functional foods and beverages have referred to various exotic or antioxidant species as
superfruits, some of which are included in the list below.
Apples – quercetin, catechins, tartaric acid
Açaí berries – dietary fiber, anthocyanins, omega-3, omega-6, beta-sitosterol. Açaí is the highest scoring plant food (spices excepted) for antioxidant ORAC value
Dried apricots
Artichoke – silymarin, caffeic acid, ferulic acid
Brassicates: kale, cabbage, brussels sprouts, cauliflower – lutein
Carrots – beta-carotene
Cocoa – flavonoids, epicatechin
Purple corn – anthocyanins
Cranberries – ellagic acid, anthocyanins
Eggplant
Gac – beta-carotene, lycopene
Goji (wolfberry) - ellagic acid, β-carotene, β-cryptoxanthin, zeaxanthin, lutein, lycopene, riboflavin, vitamin C, copper, selenium, zinc, protein
Pink grapefruit – lycopene
Red grapes and wine – quercitin, resveratrol, catechins, ellagic acid
Green tea – quercetin, catechins, oxalic acid
Mangos – cryptoxanthin
Mangosteen - xanthones
Nuts and seeds – resveratrol, phytic acid, phytosterols, protease inhibitors
Porridge oats soluble fibre magnesium, zinc
Okra -- beta carotene, lutein, zeaxanthin
Olive oil – monounsaturated fat, hydroxytyrosol, oleuropein, oleocanthal
Onions – quercetin, thiosulphonates
Papaya – cryptoxanthin
Bell peppers – beta-carotene, vitamin C
Pomegranate - vitamin C, tannins, especially punicalagins
Pumpkin – lignans, carotene
Quinoa dietary fiber, protein without gluten with balanced essential amino acids
Sea buckthorn - vitamin C, tocopherols, carotenoids, polyphenols, polyunsaturated fatty acids
Sesame - lignans
Shiitake mushrooms
Spinach – oxalic acid, lutein, zeaxanthin
squash
Watermelon – lycopene zeaxanthin, sulphoraphane, indole-3-carbinol
Spirulina - beta-caroteneFurther Information
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